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Weight Management Study

Sunshine Melbourne

Do you have obesity or are you living with overweight and weight-related health conditions? 

You may be eligible to join a clinical study evaluating a potential new once-weekly treatment, designed to support long-term weight management. 

By taking part, you may gain access to a new investigational treatment, receive regular health checks, and contribute to research that may help shape future care.

Description

What to expect

Study details

Ages

18 years or older

Duration

The study runs for approximately 70 weeks and includes 14 scheduled clinic visits and 6 phone visits. In addition to clinic visits, participants will also be required to attend lifestyle counselling sessions on healthy eating and physical activity. If you have prediabetes at the start of the study, you may be invited to take part in a 2-year extension phase for additional follow-ups.

Compensation

Participants will be compensated for reasonable expenses associated with study visits.

Eligibility Criteria

You may qualify for this study if you:

  • Are 18 years or older
  • Living with obesity with a BMI ≥30 OR
  • Overweight with a BMI  ≥27 AND have at least one of the following:

-            High Blood Pressure (Hypertension)

-            High Cholesterol (Dyslipidemia)

-            Sleep apnea

-            Cardiovascular disease (e.g., Heart failure, heart disease, history of stroke or heart attack)

  • Have not been diagnosed with diabetes (people with prediabetes may be eligible)

Other criteria apply. A member of our team will check if this study is a good fit for you.

Locations

Sunshine Melbourne

Description

Obesity and overweight are common, long-term health conditions in which the body carries excess weight that can place strain on organs, joints and everyday functioning. Many people experience symptoms such as low energy, breathlessness, disturbed sleep, or discomfort with movement. 

These conditions are incredibly prevalent, affecting millions of adults worldwide and impacting physical health, emotional wellbeing, and confidence. They can also influence daily life, from social engagement and work to self-esteem and overall quality of life.

Obesity and overweight are typically managed through healthy eating, increased physical activity, behavioural support, and sometimes medication or surgery when appropriate. While these approaches can help, many people find long-term weight management challenging. This is why ongoing research is exploring new treatment options that may offer safer, more sustainable support.

This study is exploring whether a once-weekly injection may help support long-term weight management alongside healthy eating and physical activity. It works by targeting pathways involved in appetite, eating behaviours, and metabolic regulation.

Researchers aim to understand whether the investigational treatment can:

  • Support meaningful reductions in body weight over time
  • Help improve appetite control
  • Enhance overall wellbeing and quality of life
  • For participants with prediabetes: help delay or reduce progression to type two diabetes

What to expect

Participants will be randomly assigned to receive a once-weekly injection of either:

  • The investigational treatment
  • A placebo (inactive substance)

Alongside the study medication, all participants will receive lifestyle guidance on healthy eating and physical activity. 

You will visit the clinic regularly for health assessments, including weight measurements and vital signs, blood tests, questionaries about wellbeing and eating behaviour, and general check-ups. Your safety and well-being will be closely monitored by a professional clinical team.

Why join this clinical research study?

- Gain early access to new potential treatments at no cost

- Contribute to research that could help others living with obesity or overweight

- Learn better ways to manage your health

- Receive health checks and advice from our professional medical team

Your privacy is important. All personal information will be kept strictly confidential.

Register your interest today.

Please note that this study has now closed. However, we encourage you to pre-register your interest for upcoming weight loss studies here.

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